Tue.May 06, 2025

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Low-dose clonidine infusion to improve sleep in postoperative patients in the high-dependency unit. A randomised placebo-controlled single-centre trial

Critical Care North Hampton

Explore how low-dose clonidine improves sleep in postoperative patients, with significant findings from a randomized trial in a high-dependency unit.

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Seizure and Tachycardia

Dr. Smith's ECG Blog

This was written by one of our fantastic Emergency Medicine 3rd year residents, Emily Ferrari: A young man presented with AMS and seizure like activity. EMS called by PD from a scene, where the patient had been seen ingesting powder and pills, then began acting more erratically. He was seizing on arrival to the ED, but this ceased after 5mg Versed given by medics.

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emDOCs Podcast – Episode 119: Left Ventricular Outflow Tract Obstruction

EMDocs

Today on the emDOCs cast with Rachel Bridwell, MD, and Brit Long, MD ( @long_brit) , we cover left ventricular outflow tract obstruction, or LVOTO. Episode 119: Left Ventricular Outflow Tract Obstruction Underlying Principles LVOTO occurs secondary to the systolic anterior motion (SAM) of the mitral valve (MV) Blood velocity increases due to narrowed LV outflow, forcing outflow tract and mitral valve in closer proximity 1 Venturi effect causes the mitral valve to lift anteriorly towards increase

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Leonardo Gigli

Life in the Fast Lane

Mike Cadogan Leonardo Gigli Leonardo Gigli(1863-1908) was an Italian surgeon and gynaecologist.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Two Important Concepts in Medical Practice Emerged from the Comments Yesterday

Sensible Medicine

I enjoyed reading the comments on yesterday's post regarding the positive results of the ESSENCE trial of semaglutide vs placebo in patients with metabolic dysfunction-associated steatohepatitis (MASH). Thank you to those who took the time to write. I wanted to share some very brief thoughts on two basic tenets of medical practice that emerged from the thoughtful commentary.

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Male Partner and Bacterial Vaginosis

Emergency Medicine Education

Bacterial vaginosis (BV) can sometimes be challenging to treat effectively. While standard oral antibiotics, such as metronidazole, are generally effective, some cases require switching to clindamycin for better outcomes. A recent open-label randomized controlled trial published in the New England Journal of Medicine in March 2025 evaluated the treatment of male partners with oral metronidazole and topical clindamycin cream.

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Don’t Write This In Your PI Committee Minutes!

The Trauma Pro

One of the more poorly understood concepts in trauma performance improvement is the focus of the process. Are we really discussing the patient who had a quality issue? I occasionally see something like the following in the published multidisciplinary trauma PI committee minutes: “Although an opportunity for improvement was found, it was non-contributory and had no impact on patient outcome.” Unfortunately, the true purpose of the committee discussion has been lost.

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