RebelEM

FEBRUARY 29, 2024

1, 2 Its occurrence often portends worse outcomes in intubated patients, whose projected hospital course was already tenuous. SECONDARY OUTCOMES At day 28 , ceftriaxone group had (vs placebo): Lower VAP risk (20% vs 36%); hazard ratio 0.62 4, 8 Paper: Dahyot-Fizelier, C.,

CDC 99

CDC Outcomes Radiology Radiology 99

Taming the SRU

JUNE 12, 2023

Finally, a randomized-control trial found that prophylactic antibiotics for dog bite wounds did not statistically change infection outcomes and was not cost-effective, recommending that prophylactic antibiotics only be used in high-risk wounds [12]. Clinical Infectious Diseases. Academic Emergency Medicine. 2007;14(5).

Infectious Diseases 94

Infectious Diseases Emergency Department Administration Academics 94

Sensible Medicine

JUNE 6, 2023

Two nearly identical trials of the monoclonal drug aducanumab, ENGAGE and EMERGE, had disparate outcomes: ENGAGE showed no benefit and EMERGE showed that the drug slowed decline. This seemed important to consider, and so we looked at whether outcomes in trials of monoclonal antibodies for AD correlated with rates of ARIA.

Outcomes 84

Outcomes Infectious Diseases Research Academics 84

Taming the SRU

AUGUST 30, 2023

A 2011 meta-analysis in the journal of Academic Emergency Medicine found ESR, CRP, and PCT were not acutely useful in the diagnosis of septic arthritis due to wildly varying sensitivities and specificities between studies. They recommend synovial joint aspiration and analysis for bacteria (and leukocytes) to diagnose SANJO [28].

Infectious Diseases 78

Infectious Diseases Sepsis Emergency Department Point-of-Care Testing 78

PulmCCM

OCTOBER 30, 2023

Professional Medical Societies Call for Elimination of SEP-1 The Infectious Diseases Society of America (IDSA), along with societies for emergency medicine physicians and hospitalists, are again speaking up about the ongoing policy experiment known as the Centers for Medicare and Medicaid Severe Sepsis/Septic Shock Management Bundle (SEP-1).

Sepsis 52

Sepsis Shock Hospitals Outcomes 52

ALiEM

AUGUST 21, 2023

Risk factors for poor outcomes include immunocompromise (HIV, diabetes, immunosuppression), intravenous drug use, peripheral vascular disease, and polymicrobial infection. Antibiotics should target gram-positive organisms (Staphylococcus, including MRSA, and Streptococcus). Pang HN, Teoh LC, Yam AKT, Lee JYL, Puhaindran ME, Tan ABH.

Academics 52

Academics Outcomes Hospitals Wellness 52