The Bottom Line
JUNE 19, 2023
In adult patients with major trauma, who are at risk for trauma-induced coagulopathy does early administration of 1g of tranexamic acid (TXA) followed by an infusion of 1g over 8 hours, compared with placebo, increase survival with a favourable functional outcome at 6 months?
Don't Forget the Bubbles
JUNE 19, 2023
You are asked to see a baby boy in the labour ward. He was born at 38 weeks and 5 days gestational age and weighs 2600 grams. His mother is healthy, but she does mention that her first-born daughter was also small. She weighed 2570 grams at 39 weeks and is now perfectly healthy. The parents are of South-Asian descent. There were no issues during the pregnancy, and estimated fetal growth by ultrasound was constant.
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First 10 EM
JUNE 19, 2023
The internet is alive with rumors of a simple, cheap, low-risk cure for long COVID. Sound too good to be true? That’s because it almost certainly is. Let’s talk about this COVIT-OUT trial and what it says about metformin. The paper Bramante CT, Buse JB, Liebovitz DM, et al. Outpatient treatment of COVID-19 and incidence […] The post No, metformin is probably not the cure for long COVID appeared first on First10EM.
Emergency Live
JUNE 19, 2023
Myocarditis is an inflammation of the heart muscle that affects the middle layer of the heart wall, the muscular tonaca called the myocardium The post Inflammations of the heart: myocarditis appeared first on Emergency Live.
RebelEM
JUNE 19, 2023
Background: Injuries are a major cause of death worldwide. Hemorrhage accounts for about 1/3 of all trauma deaths and as such, it should be our goal to find treatments to decrease death from hemorrhage. Our bodies have a finely tuned system that allows blood to flow freely and not clot too easily while also allowing the body to form clots when needed.
Emergency Live
JUNE 19, 2023
Kleptomania is included in the Manual of Mental Disorders (DSM-IV TR) under Impulse Control Disorders and is characterised by "the recurrent inability to resist the impulse to steal objects that have no personal utility or commercial value" The post Kleptomania: causes, symptoms, diagnosis and treatment appeared first on Emergency Live.
Sensible Medicine
JUNE 19, 2023
The specific story includes yet another failure of oseltamivir (Tamiflu) to provide benefit in the treatment of influenza. The larger story is why some therapies persist in the absence of any evidence of benefit. Sensible Medicine is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber.
Emergency Care Today brings together the best content for emergency care practitioners from the widest variety of industry thought leaders.
EM Ottawa
JUNE 19, 2023
Methodology: 4/5 Usefulness: 3.5/5 Bouzat P, et al. JAMA. 2023 Mar 21:e234080. doi: 10.1001/jama.2023.4080. Question and Methods: This double-blind, randomized, placebo-controlled superiority trial aimed to assess whether 4F-PCC decreases 24hr blood product consumption for trauma patients at risk of massive transfusion. Findings: There was no statistically significant difference in median total 24hr blood product […] The post Efficacy and Safety of Early Administration of 4-Factor Pro
Emergency Live
JUNE 19, 2023
Mitral stenosis is a narrowing (stenosis) of the mitral valve of the heart, which impairs the regular blood flow through the orifice located between the left atrium and the left ventricle The post Diagnosis of mitral stenosis? Here's what's happening appeared first on Emergency Live.
Medagadget
JUNE 19, 2023
Researchers at Rockefeller University have developed a cell culture platform in which to grow ‘lung buds’ from human embryonic stem cells. The tiny structures are similar to the lung buds that form during fetal development, and they contain tiny airways and alveoli. The researchers create the structures in a bio-reactor style device that is furnished with microfluidic chips in which the lung buds grow.
Emergency Live
JUNE 19, 2023
Multiple sclerosis is a neurodegenerative disease that affects the central nervous system and can cause disruption of signals between the brain, spinal cord and optic nerves, leading to a wide range of symptoms The post Multiple Sclerosis: Definition, Symptoms, Causes, Diagnosis, and Treatment appeared first on Emergency Live.
Medagadget
JUNE 19, 2023
Researchers at the University of Pennsylvania have developed nanorobots that can travel to the site of a fungal infection under the influence of an external magnetic field, bind to the fungal cells, and then release reactive oxygen species to completely destroy the fungus. The tiny particles are an example of catalytic nanoparticles, which the researchers have dubbed ‘nanozymes’.
Emergency Live
JUNE 19, 2023
Guyon's syndrome is a pathology characterized by irritation of the ulnar or cubital nerve at the wrist, in the area between the pisiform bone and the unciform process The post Guyon's canal syndrome, an overview of irritation of the ulnar or cubital nerve of the wrist appeared first on Emergency Live.
Science Based Medicine
JUNE 19, 2023
Last month, Dr. Rashid Buttar, a prominent antivax "integrative medicine" practitioner, died suddenly. Because he hadn't been vaccinated, antivaxxers struggled mightily to reconcile his death with their conspiracy theory about COVID-19 vaccines killing thousands "suddenly." It turns out, however, that that Dr. Buttar had not been a well man since 2016 and was as much a victim of quackery as his patients had been.
Emergency Live
JUNE 19, 2023
Scleroderma sees its peak onset in patients between the ages of 45 and 65 and, as is often the case with autoimmune diseases, it is women who are more affected, with a clear disproportion of 3-5:1 The post Scleroderma: definition, causes, symptoms, diagnosis and treatment appeared first on Emergency Live.
Maria Yang, MD
JUNE 19, 2023
Here’s a small selection of things I humbly recommend for your consideration: The Disadvantages of an Elite Education. “Our best universities have forgotten that the reason they exist is to make minds, not careers.” (Incisive writing from William Deresiewicz, who is also the author of one of my favorite essays, Solitude and Leadership.
American Medical Compliance
JUNE 19, 2023
Several states have recently approved the extension of postpartum Medicaid coverage beyond the usual two-month period. This decision marks a significant milestone in addressing the critical needs of new mothers and underscores a growing recognition of the importance of comprehensive postpartum care. By providing extended Medicaid coverage, states are taking a proactive approach to safeguarding the well-being of mothers during this vulnerable period.
Emergency Live
JUNE 19, 2023
A pinguecula is a non-cancerous degenerative formation that forms on the conjunctiva (protective mucous membrane lining the eyeball and the inside of the eyelids) The post Eye diseases: overview of pinguecula appeared first on Emergency Live.
PulmCCM
JUNE 19, 2023
Could metformin prevent long Covid? In the previously published COVID-OUT study, over 1400 patients with a new diagnosis of Covid-19 (symptoms + PCR) were randomized to receive metformin, fluvoxamine, ivermectin, placebo, or any combination thereof (six arms). No drug or combination improved the primary outcome (a composite outcome of hypoxemia, visit to the emergency department, hospitalization, or death).
Dr. Smith's ECG Blog
JUNE 19, 2023
Written by Kaley El-Arab MD, edits by Pendell Meyers and Stephen Smith A 61-year-old male with hypertension and hyperlipidemia presented to the emergency department for chest tightness radiating to the back of his neck that has been intermittent for the past day or two. Here is his triage ECG which was obtained at 20:34 during active pain. What do you think?
EMergucate
JUNE 19, 2023
Repeat for lab case 351, Question 1: PH = 7.53, that is mild alkalaemia pCO2 = 25 mmHg, that is low (<40), so we have respiratory alkalosis.
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