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Killer antibiotic stewardship strategy? (The ADAPT-Sepsis trial)

First 10 EM

Optimizing sepsis care, including the appropriate length of antibiotic therapy, is an important goal. So should we be willing to allow an increase in mortality to reduce total antibiotic use, as the ADAPT-Sepsis non-inferiority design seems to imply? The ADAPT-Sepsis trial) appeared first on First10EM.

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EM@3AM: Stercoral Colitis

EMDocs

Well keep it short, while you keep that EM brain sharp. A 73-year-old female is brought in by EMS for abdominal pain, vomiting, and weakness for two days. 2-4, 6 If there is a concern for perforation or sepsis, surgical consultation, blood cultures, empiric antibiotics, and fluids are recommended.

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Clinical Conundrum: Should We Always Treat Fever in Patients with Sepsis?

RebelEM

Bottom Line Up Top: There doesnt appear to be a morbidity or mortality benefit to treating fever in sepsis and fever may have a protective effect. A large observational study of > 2000 patients found an association with fever at presentation and ICU survival for patients with severe sepsis or septic shock ( Sunden-Culberg 2017 ).

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EM@3AM: Leukopenia

EMDocs

Well keep it short, while you keep that EM brain sharp. PCP Pneumonia, Sepsis) can be discharged with initiation of Antiretroviral Therapy in consultation with Infectious Disease (ID) physician with full ID evaluation outpatient. 2nd edition. Geneva: World Health Organization; 2016. 2, CLINICAL GUIDELINES: HIV DIAGNOSIS.

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Pre-Hospital Antibiotics in Sepsis?

RebelEM

Background: Sepsis remains one of the leading causes of morbidity and mortality. Prehospital Administration of Broad-Spectrum Antibiotics for Sepsis Patients: A Systematic Review and Meta-Analysis. It is well-established that earlier recognition and treatment can lead to better outcome for these patients . Health Sci Rep 2022.

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Finally, a cure fore sepsis: Herbs

First 10 EM

Can herbs cure sepsis?

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MDCalc Wars: NEXUS Criteria Vs Canadian C-Spine Rules

RebelEM

Rethinking Antibiotic Duration in Sepsis The BALANCE Trial Current IDSA guidelines for sepsis recommend individualized durations of antibiotic. Trauma Read More Is 7 Days Enough? Infectious Disease Read More TNK vs tPA The ORIGINAL Trial The American Heart Association and the European Stroke Organization have.

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