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The NICO Trial: NIV in Comatose Patients with Acute Poisoning

RebelEM

Additionally, intubation can risk hemodynamic instability as well as hypoxemia from the procedure itself. There has been no high level evidence to help guide practice until now…the Non-Invasive Airway Management of Comatose Poisoned Emergency Patients (NICO) trial. Paper: Freund Y et al.

Poisoning 130
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2023 AHA Update on Management Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning

EMDocs

Author: Brit Long, MD (@long_brit) // Reviewed by Alex Koyfman, MD (@EMHighAK) The American Heart Association 2023 Guideline for managing cardiac arrest or life-threatening toxicity due to poisoning was recently released. Opioid overdose remains the leading cause of cardiac arrest due to poisoning in North America.

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ToxCard: Bupropion

EMDocs

3 Bupropion blocks the reuptake of dopamine and norepinephrine, as well as antagonizes acetylcholine at nicotinic receptors. Bupropion lowers the seizure threshold and even at therapeutic doses patients can have seizures. 6 In one study, almost all patients who went on to develop seizures had tachycardia prior to the seizure.

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ACMT Toxicology Visual Pearl: The Bark with Some Bite

ALiEM

How can people become poisoned with willow bark? Cases of toxicity have been reported following ingestion of supplements as well as ingestion of willow bark tea [4,5]. With severe toxicity, patients can have altered mental status, seizures, hyperthermia, and pulmonary edema.

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Case Report: Toxic Hypoglycemic Syndrome

ACEP Now

1 In severe cases altered mental status, seizures, coma, or even death have been observed. 8 Diagnosis and Treatment Food poisoning may result in a similar clinical manifestation as Toxic Hypoglycemic Syndrome. Poison control was consulted, and they concurred with the diagnosis of THS. References Katibi OS, Olaosebikan R, et al.

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ToxCard: Chronic Organophosphate Toxicity

EMDocs

Organophosphate poisoning in agriculturally centered communities has developed into a public health concern in developing countries, poisons millions and kills hundreds of thousands each year worldwide and is a reason why understanding organophosphate toxicity has become a critical addition to our knowledge of toxicology.

PPE 69
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Fearsome Foliage - An Overview of Toxic Plants

Taming the SRU

Poison centers across the United States receive over 100,000 reports of exposures to toxic plants annually. More serious poisonings typically involve adults who ingest plants in larger quantities for recreational, self-harm, foraging or medicinal purposes (1). Spring has sprung. and so have many species of toxic plants! Decontaminate.