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The 73rd Bubble Wrap

Don't Forget the Bubbles

Article 1: Does rapid diagnostic testing for Malaria work? A Diagnostic Accuracy Study to Evaluate Standard Rapid Diagnostic Test (RDT) Alone to Safely Rule Out Imported Malaria in Children Presenting to UK Emergency Departments. This puts a high financial and resource cost on front-line settings.

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Imported Malaria

Pediatric EM Morsels

This is typically only widely available in endemic countries (Forgie 2022) More recently there has been a deletion in the Pfhrp 2/3 gene in some P.

Seizures 240
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Cholera: ED presentation, evaluation, and management

EMDocs

16 In resource-constrained settings, rapid diagnostic tests (RDTs) on stool samples offer a viable option. Field evaluation of a locally produced rapid diagnostic test for early detection of cholera in Bangladesh. 13 Dark-field microscopy can be used to rapidly detect V. cholerae O1 and O139 serogroups.

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Malaria

Mind The Bleep

Investigations EDTA blood (ie an FBC bottle) should be sent urgently for thick and thin films Most laboratories will also perform a rapid diagnostic test (lateral flow), which has quite good sensitivity for P falciparum and reasonable sensitivity for P vivax If the rapid test is negative, consider alternative differentials (e.g.

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The 79th Bubble Wrap x Bristol Royal Hospital For Children

Don't Forget the Bubbles

This was a secondary outcome embedded in the Travel Fever study – a multi-centre, retrospective diagnostic accuracy study for imported malaria. This compared the reference test (standard microscopy) with the index test (standard rapid diagnostic test (RDT)).