hr 
PulmCCM
JANUARY 29, 2022
The first large, now completed, clinical evaluation of NIR-RIT is the EPIC-HR study , or the Evaluation of Protease Inhibition for COVID-19 in High-Risk patients. Stated another way, if you treat 17 patients meeting the inclusion and exclusion criteria for EPIC-HR, an instance of hospitalization or death due to COVID-19 is prevented.
First 10 EM
APRIL 22, 2024
Pfizer rushed to publish their positive study (EPIC-HR), but refused to release the results of a second simultaneous study (EPIC-SR) that was stopped (due to futility) at the exact same time. As mentioned in my most recent review, publication bias has been a major concern when trying to decide whether to prescribe paxlovid.
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Mind The Bleep
FEBRUARY 27, 2024
She is tachycardic with HR 160, she has cool peripheries with CRT 3 seconds and her BP is in the normal range for her age. She weighs 16kg Select the management from the options below and scroll down for the correct answer [A] Fluid bolus of 380ml, then start IV fluids at 60ml/hr. However it is not one size fits all. She weighs 20kg.
Mount Sinai EM
JULY 30, 2023
Goal: reduce HR and BP Mechanism: mitigates adrenergic surge to improve symptoms. In addition, at high doses it inhibits the conversion of T4 to T3 PO Dose: 60 to 80 mg q4-6 hr, titrated to achieve rate control while ensuring blood pressure remains stable. to 1 mg over 10 minutes followed by 1 to 2 mg over 10 minutes q2-3 hr.
JournalFeed
MARCH 13, 2021
It’s the JournalFeed Podcast for the week of Mar 8-12, 2021. We cover the physiologically difficult airway, which video laryngoscope is best, the correlation of body temperature with heart rate, the superiority of the Canadian TIA score over ABCD2, and a revisit of the Ten Commandment of Emergency Medicine.
Sensible Medicine
JANUARY 15, 2024
Five mg of IV atenolol was given immediately and repeated again in 10 minutes if the HR and BP were ok. If after another 10 minutes, the HR > 40 bpm, oral atenolol 50 mg was given. And if possible based on HR and BP, the patient received 100 mg daily of atenolol. Twelve hours later another 50 mg of oral atenolol was given.
Don't Forget the Bubbles
NOVEMBER 27, 2023
NaCl, his HR came down a little, but the effect was short-lived. He has an HR of 190/min, and his BP is 85/35 mmHg. In the context of developing cardiovascular compromise, the body will increase the HR as part of a package of compensation measures to maintain BP. The HR falls to 180/min, and BP improves to 95/45 mmHg.
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