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ICU Physiology in 1000 Words: Phenylephrine Pushes & Stroke Volume

PulmCCM

To focus matters, the hemodynamic variable under consideration is the stroke volume [SV]; in other words, how does a push of phenylephrine affect SV? By contrast, ephedrine also effectively treated hypotension, but preserved HR, SV, CO and SctO2. Might phenylephrine’s SV-depressant effect be due to increased afterload?

Stroke 40
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Another Piece of Equipment with Racial Bias

RebelEM

Paper: Bhavani SV et al. References: Bhavani SV et al. We have already covered issues with pulse oximetry potentially missing hypoxemia in Black patients on REBEL EM ( Link is HERE ). Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements in Hospitalized Patients.

EMS 52
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ACMT Toxicology Visual Pearl: The Black Eschar

ALiEM

0000000000000446 Hendricks KA, Wright ME, Shadomy SV, et al. Does anthrax antitoxin therapy have a role in the treatment of inhalational anthrax? Current Opinion in Infectious Diseases 31(3):p 257-262, June 2018. | DOI: 10.1097/QCO.0000000000000446 Emerg Infect Dis. 2014;20(2):e130687. 4th edition.

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ACMT Toxicology Visual Pearl: Needle to Necrosis

ALiEM

DOI Malayala SV, Papudesi BN, Bobb R, Wimbush A. PMID: 35020700 Knopf, A. Effects of Xylazine in Illicit Fentanyl Supply: Report from OASAS. Alcoholism & Drug Abuse Weekly. 2023;35(26):6-7. Published 2023 June 30. Xylazine-Induced Skin Ulcers in a Person Who Injects Drugs in Philadelphia, Pennsylvania, USA. 2022;14(8):e28160.

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The SPEED Protocol: Using Ultrasound To Detect Acute Aortic Dissection

ACEP Now

Diercks DB, Promes SB, Schuur JD, Shah K, Valente JH, Cantrill SV. Presentation, diagnosis, and outcomes of acute aortic dissection: 17-year trends from the International Registry of Acute Aortic Dissection. J Am Coll Cardiol. 2015;66(4):350-358. Ann Emerg Med. 2015;65:32-42.

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Xylazine: “Zombie Drug” is an Emerging Threat

ACEP Now

Malayala SV, et al. N Engl J Med. 2023; 15;388(24):2209-2212. Rodríguez N, et al. GC-MS confirmation of xylazine (Rompun), a veterinary sedative, in exchanged needles. Drug and alcohol dependence. 2008;96(3):290–293. Xylazine-induced skin ulcers in a person who injects drugs in Philadelphia, Pennsylvania, USA. 2022;14(8):e28160.

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emDOCs Podcast – Episode 90: Hypokalemic Periodic Paralysis

EMDocs

Tan SV, Matthews E, Barber M, et al. Electromyography guides toward subgroups of mutations in muscle channelopathies. Ann Neurol 2004;56:650–661. McManis PG, Lambert EH, Daube JR. The exercise test in periodic paralysis. Muscle Nerve 1986;9:704–710. Refined exercise testing can aid DNA-based diagnosis in muscle channelopathies.