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Goal-Oriented, Bundled Care For Intracerebral Hemorrhage Improves Outcomes

ACEP Now

Both INTERACT-2 and ATACH-2 showed no statistical difference in their primary outcome between intensively lowering the BP and a less-intensive strategy. Background There have been a couple of large and influential trials published on BP management after an intracranial hemorrhage (ICH). Reference Ma LM, Hu X, Song L, et.

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Functional outcomes after survival from critical illness (Review)

PulmCCM

Functional outcomes after survival from critical illness , and the constellation of disabilities and dysfunction now termed post-ICU syndrome, are getting more attention. There’s scarce proof from randomized trials that reducing delirium in and of itself improves outcomes.

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Heads Up! There is No Association with Improved Outcomes for Head Up CPR: Why We Must Read Past the Abstract

RebelEM

Background: There are only two interventions that have been proven in the medical literature to improved outcomes in cardiac arrest: high-quality CPR and early defibrillation. Over the years, we as a scientific community have worked extensively to find other interventions that improve outcomes. However, human data is sorely lacking.

CPR 52
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Don’t Use Lytics in Mild Stroke, Part 3

EM Literature of Note

Well, PRISMS demonstrated unfavorable results. MARISS tried to ascertain predictors of poor outcome in mild stroke, and intravenous thrombolysis was not associated with an effect on the primary outcome. Now, again, we examine thrombolysis in “mild” stroke, in this case, NIHSS ≤3 – and fail.

Stroke 120
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When EHR Interventions Succeed … and Fail

EM Literature of Note

Each of these disease states has well-defined pathways for “optimal” therapy and escalation. The most notable feature of this trial is the simple, negative topline result – rollout of this intervention had no reliably measurable effect on patient-oriented outcomes relating to disease progression or acute clinical deterioration.

Outcomes 101
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Pre-Hospital Antibiotics in Sepsis?

RebelEM

It is well-established that earlier recognition and treatment can lead to better outcome for these patients . Three outcomes were evaluated, with none being deemed the primary outcome. Background: Sepsis remains one of the leading causes of morbidity and mortality. to 0.97; p = 0.02 to 2.07; p = 0.91 to 12.33; p = 0.26

Sepsis 119
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SGEM#284: Might as Well Jump, but We would Recommend a Parachute

The Skeptics' Guide to EM

Case: A 32-year-old woman with no previous medical history calls you while a passenger on a […] The post SGEM#284: Might as Well Jump, but We would Recommend a Parachute first appeared on The Skeptics Guide to Emergency Medicine. Secondary Outcomes: Health status and subgroup analysis based on type of aircraft or previous parachute use.