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Giving TXA Via An Intraosseous Line?

The Trauma Pro

A few years ago, the CRASH-2 study lent support for using tranexamic acid (TXA) in select trauma patients to improve survival. The US military has adopted its routine use at forward combat hospitals. Bottom line: This was a very simple and elegant study. But what if you don’t have IV access?

Military 279
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Improving Your Critical Appraisal Skills #3

Sensible Medicine

I love case control studies. When done well, they are simple, relatively easy to perform studies, that can be hugely impactful, usually by suggesting that an exposure is harmful. Case control studies have saved millions of lives, demonstrating the adverse effects of substances such as tobacco smoke, DES, and dexfenfluramine.

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A (different) perspective on statins in the primary prevention of heart disease

Sensible Medicine

He cites a study in the New England Journal of Medicine that shows the effects of reducing cardiovascular events gets larger over time. Observational studies of long-term statin exposure suggest that the relative risk of developing diabetes mellitus could range from 46% after 5.9

Stroke 145
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Use Of Radio-opaque Markers In Penetrating Trauma

The Trauma Pro

I concur that we have techniques like CT scan available to us now that provide an excellent view of the penetration trajectory. The skin wound is usually apparent on the scan, but may be improved with the use of a CT-approved marker. For now, keep using those markers!

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Three New Studies Show the COVID Vaccines Are Very Safe for Children

Science Based Medicine

Three new studies tell us what we already knew- vaccine isn't perfect, but it's far safer than the virus for children. The post Three New Studies Show the COVID Vaccines Are Very Safe for Children first appeared on Science-Based Medicine.

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Robotic Ankle Helps with Postural Control in Amputees

Medagadget

So far, the system has been shown to assist with postural control, which in this context refers to the many complex and unconscious movements that the muscles in our legs make to maintain balance and keep us upright, even when we are largely standing still.

Research 105
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How Good is Ultrasound at Diagnosing PTA?

RebelEM

Question: How well does the US perform in diagnosing PTA compared to CT, needle aspiration, or Incision and Drainage? Two investigators independently assessed and screened all studies for eligibility. Two reviewers independently assessed study quality using the QUADAS-2 tool Authors were contacted for any missing or unreported data.